In skilled and careful hands, a hammer and chisel can form beauty out of boulders. However in the tactile hands of the masses, that same hammer and chisel create bit more than gravel and dust. Contract, like the psych-meds we here discuss, had the potential to help, when used and skillfully sparingly.
But the FDA rightfully acknowledged that we physicians as a whole, and the minute-rice masses we serve cannot be respected using this type of hammer and chisel. Across 3475 patients exposed, and 2313 patients many years of exposure, Contrave regularly demonstrated clinically meaningful weight loss. And I do emphasize “clinically meaningful” to Dr. John contention. Across all scholarly studies, patients on Contrave lost an average of 5-9% of their body weight.
They decreased A1C by .6%. They reduced CRP by 7-20%. They lost 11% surplus fat compared to 4% for placebo…and they lost 15% visceral surplus fat compared to 5% placebos. Those are some damn decent amounts…and if you look at the ongoing work from Avenell, Eliat-Adar, or the united states Cancer Prevention Study…you could argue those are life-saving quantities. Those were 3475 potentially fortunate patients to have been placed on Contrave.
- Walking in place
- Room: Grand Ballroom West
- 1/2 teaspoon Garlic, crushed
- It is a valid solution for quickly shedding a few pounds
About half of these lost 5% or even more of their body weight. But think about the rest…the 12-20% who lost no weight and may have actually gained weight? Or think about the relative threat of ischemic cardiovascular disease at 1.3 for Contrave over placebo? Addressing those 3475 patients…for the most part back again, they were obese but not too ill.
The list of excluding illnesses, laboratory ideals, and medications is bigger than…(insert inappropriate excess fat joke here). It is stated by me is most beneficial to let Contraves carcass lay decomposing at the feet of the FDA. For all those willing to review the science…for those willing to be selective…for those willing to be cautious…it’s mighty easy to RX generic bupropion sr and naltrexone together. I use this combo with reasonably good results. But like most the psychiatrist, I convince myself that I know how to wield my hammer and chisel and choose the right boulder…often ignoring the pile of gravel and dust that gathers on my shoes.
I had Theodore’s blood work done today and his ALT went from 773 down to 180 u/L. I am happy and happy extremely. I know this is working. You have preserved my little baby and a cost can’t be placed by you on that! The veterinarian could not know how April ALKP has decrease from 1,999 on June 23, 2016 to 304 currently August 19, 2016, a whooping 1,695 or 84.79 % in two months. Thank you for all the help again.
Amazing – that’s all I can say! Further update: April proceeded to go for a dental care cleaning a few days ago (past due Sept 2016 – the first one in a couple of years. The veterinarian was surprised to find that her ALKP was 166.00 !!!! Quite a distance down from 2,000 some time ago. Incredible, that’s all she could say! UPDATE HALF A YEAR LATER: Another Aced Lab record! Amy’s owner STOPPED having Amy tested every month – which I’m sure her Vet originally recommended – but was the waste materials of money! Saxon’s Bile Acid Test quantities and liver organ enzymes were off the charts!
Now 2 yrs later the veterinarian says this “I am looking at Saxon’s blood panel and I am completely blown away at what I see. This dog is within absolute perfect health. I have great news! After four months of exactly following your eating regimen and using the recommended supplements, Tanner’s ALT level proceeded to go from 219 to 39! It’s now the lowest it’s been since I’ve been tracking it for four years.